Lei Ren, PhD

Associate Professor of Radiation Oncology
Department: Radiation Oncology
Division: Radiation Physics
Address: 04209 Radiation Physics
P.O. Box 3295 DUMC
Durham, NC 27710
Office Phone: (919) 668-0489
Email: lei.ren@duke.edu

Research Interests

Dr. Ren's research interests include imaging dose reduction using digital tomosynthesis (DTS), cone-beam CT (CBCT) scatter correction, novel DTS/CBCT image reconstruction methods using prior information and motion modeling, image guided radiation therapy (IGRT), deformable image registration, patient clinical objective QA methods, stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT).       


Mayyas, E; Chetty, IJ; Chetvertkov, M; Wen, N; Neicu, T; Nurushev, T; Ren, L; Lu, M; Stricker, H; Pradhan, D; Movsas, B; Elshaikh, MA. Evaluation of multiple image-based modalities for image-guided radiation therapy (IGRT) of prostate carcinoma: a prospective study. 2013;40:041707. Abstract

Kim, J; Wen, N; Jin, J-Y; Walls, N; Kim, S; Li, H; Ren, L; Huang, Y; Doemer, A; Faber, K; Kunkel, T; Balawi, A; Garbarino, K; Levin, K; Patel, S; Ajlouni, M; Miller, B; Nurushev, T; Huntzinger, C; Schulz, R; Chetty, IJ; Movsas, B; Ryu, S. Clinical commissioning and use of the Novalis Tx linear accelerator for SRS and SBRT. Journal of applied clinical medical physics / American College of Medical Physics. 2012;13:124-151.

Chang, Z; Wu, Q; Adamson, J; Ren, L; Bowsher, J; Yan, H; Thomas, A; Yin, F-F. Commissioning and dosimetric characteristics of TrueBeam system: composite data of three TrueBeam machines. Medical physics. 2012;39:6981-7018. Abstract

Chang, Z; Bowsher, J; Cai, J; Yoo, S; Wang, Z; Adamson, J; Ren, L; Yin, F-F. Imaging system QA of a medical accelerator, Novalis Tx, for IGRT per TG 142: Our 1 year experience. Journal of applied clinical medical physics / American College of Medical Physics. 2012;13:113-140.

Li, H; Giles, W; Ren, L; Bowsher, J; Yin, F-F. Implementation of dual-energy technique for virtual monochromatic and linearly mixed CBCTs. Medical physics. 2012;39:6056-6064. Abstract

Ren, L; Chetty, IJ; Zhang, J; Jin, J-Y; Wu, QJ; Yan, H; Brizel, DM; Lee, WR; Movsas, B; Yin, F-F. Development and clinical evaluation of a three-dimensional cone-beam computed tomography estimation method using a deformation field map. International Journal of Radiation: Oncology - Biology - Physics. 2012;82:1584-1593. Abstract

Ren, L; Yin, F-F; Chetty, IJ; Jaffray, DA; Jin, J-Y. Feasibility study of a synchronized-moving-grid (SMOG) system to improve image quality in cone-beam computed tomography (CBCT). Medical physics. 2012;39:5099-5110. Abstract

Jin, J-Y; Kong, F-M; Liu, D; Ren, L; Li, H; Zhong, H; Movsas, B; Chetty, IJ. A TCP model incorporating setup uncertainty and tumor cell density variation in microscopic extension to guide treatment planning. Medical physics. 2011;38:439-448. Abstract

Jin, J-Y; Wen, N; Ren, L; Glide-Hurst, C; Chetty, IJ. Advances in treatment techniques: arc-based and other intensity modulated therapies. Cancer Journal. 2011;17:166-176. Abstract

Jin, J-Y; Ren, L; Liu, Q; Kim, J; Wen, N; Guan, H; Movsas, B; Chetty, IJ. Combining scatter reduction and correction to improve image quality in cone-beam computed tomography (CBCT). Medical physics. 2010;37:5634-5644. Abstract

Yoo, S; Wu, QJ; Godfrey, D; Yan, H; Ren, L; Das, S; Lee, WR; Yin, F-F. Clinical evaluation of positioning verification using digital tomosynthesis and bony anatomy and soft tissues for prostate image-guided radiotherapy. International Journal of Radiation: Oncology - Biology - Physics. 2009;73:296-305. Abstract

Ren, L; Godfrey, DJ; Yan, H; Wu, QJ; Yin, F-F. Automatic registration between reference and on-board digital tomosynthesis images for positioning verification. Medical physics. 2008;35:664-672. Abstract

Ren, L; Zhang, J; Thongphiew, D; Godfrey, DJ; Wu, QJ; Zhou, S-M; Yin, F-F. A novel digital tomosynthesis (DTS) reconstruction method using a deformation field map. Medical physics. 2008;35:3110-3115. Abstract

Yan, H; Ren, L; Godfrey, DJ; Yin, F-F. Accelerating reconstruction of reference digital tomosynthesis using graphics hardware. Medical physics. 2007;34:3768-3776. Abstract

Godfrey, DJ; Ren, L; Yan, H; Wu, Q; Yoo, S; Oldham, M; Yin, FF. Evaluation of three types of reference image data for external beam radiotherapy target localization using digital tomosynthesis (DTS). Medical physics. 2007;34:3374-3384. Abstract